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A study using expertise and capabilities at the +Environmental Molecular Sciences Laboratory (EMSL) at PNNL identified a novel cyanobacterial strain that grows rapidly and is amenable to genetic manipulation – qualities that make it useful for synthetic biology and metabolic engineering applications. The research team included scientists from PNNL, Washington University in St. Louis, EMSL and the +The University of Texas at Austin. Read more at http://www.emsl.pnnl.gov/emslweb/news/ideal-microbe-industrial-purposes.<br /><br />* * *<br /><br />Cyanobacteria are of considerable interest as production organisms in biotechnology. They can grow by harvesting energy from sunlight, an abundant energy source, and they consume carbon dioxide, a greenhouse gas. However, commonly used cyanobacterial strains grow slow. Furthermore their genetic and metabolic networks are not as well understood when compared with other bacteria and yeast models used for industrial applications. This study identified a novel cyanobacterial strain that grows rapidly and is amenable to genetic manipulation that makes it ideal for a wide range of synthetic biology and metabolic engineering applications.<br /><br />In search for an ideal photosynthetic microbe for industrial purposes, researchers from Washington University in St. Louis, Pacific Northwest National Laboratory (PNNL), EMSL, the Environmental Molecular Sciences Laboratory and the University of Texas at Austin identified a fast growing cyanobacterial strain called Synechococcus elongatus UTEX 2973. To characterize this strain, they performed whole-genome sequencing at WUSTL and proteomics at EMSL, a DOE national scientific user facility.<br /><br />The researchers found the newly identified strain grows as fast as yeast, without requiring special nutrients such as vitamins. Its growth rate is not only the highest reported to date for any cyanobacterium strain, but is also more than twice as fast as a widely studied close relative. As a result, Synechococcus UTEX 2973 rapidly accumulated substantial amounts of biomass—a valuable trait in the bioenergy arena. The rapid growth of this cyanobacterial strain also facilitates genetic manipulation studies. The researchers generated two types of mutants by introducing a gene encoding a fluorescent protein and inactivating a gene involved in the regulation of light harvesting, demonstrating the newly described strain is amenable to easy, rapid genetic modification.<br /><br />The genome sequencing data showed a small number of nucleotide changes are the only significant differences between the genomes of the two closely related cyanobacterial strains, which are 99.8 percent identical in their genome sequences. These findings revealed the genetic determinants necessary for rapid growth of cyanobacterial strains of significant industrial potential. Moreover, the proteomics data will be a valuable resource for the research community because the global proteomes of the two cyanobacterial strains had never before been analyzed. Taken together, the findings demonstrate the excellent potential of Synechococcus UTEX 2973 as a cyanobacterial strain for broad biotechnological applications.<br /><br />Why is this important?  A cyanobacterial strain that can grow rapidly and is amenable to easy, targeted genetic manipulation will expedite the process of characterizing the cellular biology and genetic and metabolic networks of cyanobacteria. The strain will also enable development of new synthetic biology tools for these microbes. The newly identified strain could pave the way for widespread use of cyanobacteria for carbon sequestration, biofuel production, biosynthesis of valuable chemicals, and search for novel pharmaceuticals.

Suggested donation of $18 at the door A $36 advanced payment option includes VIP expedited registration, reserved premier seating, and a signed copy of "Remember My Soul" by Lori Palatnik, a beautifully written book that answers the question "What do we do to honor the memory of a loved one?"

Mail check payable to Aish HaTorah St. Louis, Attn: Claire Wolff, 457 N. Woods Mill Rd., Chesterfield, MO 63017 or call with credit card payment to 314-862-2474. Deadline for the $36 advanced payment option is February 14, 2014

EVENT CO-CHAIRS: Mimi Pultman & Ellie Grossman Cohen
COMMITTEE: Mimi David, Cindy Becker, Jodie Brandt Neuman, Kalanit Chappell, Elise Krug, Yael Kula, Ellen Levy Siwak, Beth Mayer, Vicki Redler Chervitz, Stephanie Ruter, Andria Simckes, Rebecca Brown, Alana Umansky Minoff and Peggy Umansky">Lori Palatnik is coming to St. Louis.<br /><br />Aish HaTorah St. Louis & Nishmah present one of the world's most inspiring teachers. Monday, February 17, 2014 at 7:30 PM
Suggested donation of $18 at the door A $36 advanced payment option includes VIP expedited registration, reserved premier seating, and a signed copy of "Remember My Soul" by Lori Palatnik, a beautifully written book that answers the question "What do we do to honor the memory of a loved one?"

Mail check payable to Aish HaTorah St. Louis, Attn: Claire Wolff, 457 N. Woods Mill Rd., Chesterfield, MO 63017 or call with credit card payment to 314-862-2474. Deadline for the $36 advanced payment option is February 14, 2014

EVENT CO-CHAIRS: Mimi Pultman & Ellie Grossman Cohen
COMMITTEE: Mimi David, Cindy Becker, Jodie Brandt Neuman, Kalanit Chappell, Elise Krug, Yael Kula, Ellen Levy Siwak, Beth Mayer, Vicki Redler Chervitz, Stephanie Ruter, Andria Simckes, Rebecca Brown, Alana Umansky Minoff and Peggy Umansky" src="http://lh3.googleusercontent.com/-MUM9UeAkj0Q/Ut7QW2cOCuI/AAAAAAAAAB4/7dDTG5MDkzM/lori.jpg" width="100" height="100" />
Expedite+STL:+St.+Louis


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In This Section - Charlotte Observer



Charlotte Observer

In This Section
Charlotte Observer
Be sure to include your name, daytime phone number, address, name and phone number of legal next-of-kin, method of payment, and the name of the funeral home/crematory to contact for verification of death. For more information about placing obituaries, ...

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FACT SHEET: Administration Announces New Commitments in Support of ... - Whitehouse.gov (press release)



FACT SHEET: Administration Announces New Commitments in Support of ...
Whitehouse.gov (press release)
... NW Training Partnership and 1199SEIU Bill Michelson Home Care Education Fund, and unions like IBEW Local Union 43, the Carpenters' District Council of Greater St. Louis and Vicinity, and UAW, are committing to expanding access to registered ...

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St. Louis Authority Is Throwing A Legal Tantrum About Rams' Stadium - SportsGrid



SportsGrid

St. Louis Authority Is Throwing A Legal Tantrum About Rams' Stadium
SportsGrid
Rams fans can pretty much stop buying merchandise. Their jerseys are probably going to be obsolete, or collectors items in 2016. St. Louis authorities involved are doing their best to dodge a public vote to expedite the building of a new stadium in St ...

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New York Giants: Analyzing the Latest NFL Draft Rumors and Reports - Bleacher Report



Bleacher Report

New York Giants: Analyzing the Latest NFL Draft Rumors and Reports
Bleacher Report
That's right, as the NFL draft draws oh so near and teams around the league are assembling their final draft boards, the rumors are flying around worse than the pollen that's polluting the Northeast this time of year. What are “those in the know ...

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2015 NFL Mock Draft 5.0: Eagles trade twice to land Marcus Mariota - CBSSports.com



CBSSports.com

2015 NFL Mock Draft 5.0: Eagles trade twice to land Marcus Mariota
CBSSports.com
12) in exchange for Sam Bradford (Philly can throw in a third-round pick to expedite the deal maybe?). The Browns own No. 19 in this draft and have their new quarterback. The Eagles own No. 12, which Kelly promptly packages with No. overall and sends ...

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10 things to know for Wednesday - Mail Tribune



10 things to know for Wednesday
Mail Tribune
U.S. TO EXPEDITE WEAPONS DELIVERIES TO SAUDI-LED YEMEN COALITION. Deputy Secretary of State Antony Blinken blames the violence on the rebels, known as Houthis, and forces loyal to former ... Voters elect two black candidates, increasing African ...

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VA pledges broad review of claims processing - 12NewsNow.Com



VA pledges broad review of claims processing
12NewsNow.Com
Rubens said she requested the payment to expedite her move to Philadelphia, but Miller suggested that Rubens did not meet the qualifications for the payment. The IG is reviewing the expenses. "At VA it's become an entitlement, in which taxpayers are ...

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Crowds throng Ferguson City Hall for a new start - Quad City Times



Quad City Times

Crowds throng Ferguson City Hall for a new start
Quad City Times
Newly elected Ferguson city councilmen Wesley Bell (left), Ella Jones, and Brian Fletcher say the Pledge of Allegiance at the start of a council meeting where they were sworn into office on Tuesday, April 21, 2015. Photo By David Carson, ...

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Ride for the Troops - Kokomo Perspective



Kokomo Perspective

Ride for the Troops
Kokomo Perspective
... it before the ride. This will help expedite the ride. The route is listed below for those who come out along the route to Waive us on. It is Goyer Road South, Southway Blvd, Albright Road, Cartwright, Center, US 31 South, 28 East, Tipton/Elwood, 37 ...

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